To help make backing out of a parking space safer, the NX has standard Rear Cross-Traffic Alert with Parking Support Brake, systems which detect vehicles approaching from the sides and can automatically apply the brakes to prevent a collision. Parking Support Brake costs extra on the Crown Signia Limited, and isn't offered on other Crown Signia models.
Both the NX and the Crown Signia have standard driver and passenger frontal airbags, front side-impact airbags, driver knee airbags, side-impact head airbags, front and rear seatbelt pretensioners, height adjustable front shoulder belts, four-wheel antilock brakes, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, daytime running lights, lane departure warning systems, blind spot warning systems, rearview cameras, rear cross-path warning, driver alert monitors and available around view monitors.
The Lexus NX achieved a “Top Safety Pick” rating from the Insurance Institute for Highway Safety (IIHS) for the 2025 model year. This recognition was based on its impressive performance in the small overlap frontal crash test, updated moderate overlap front crash test, updated side impact crash test, headlight evaluations, and pedestrian crash prevention testing. The Crown Signia has not yet been fully evaluated by the IIHS for 2025.

